Cerebral Ischemia and Infarction From Atheroemboli <100 μm in Size

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Cerebral Ischemia and Infarction From Atheroemboli <100 m in Size

Background and Purpose—To determine the importance of emboli not trapped by carotid angioplasty filtration devices, we examined fragments 100 m released with ex vivo angioplasty and asked if fragment composition and size correlated with brain injury. Methods—Human carotid plaques (21) were excised en bloc, and ex vivo carotid angioplasty was performed. Eight plaques were selected as either high...

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Inhibition of Angiotensin-Converting Enzyme Reduces Cerebral Infarction Size in Experimental-Induced Focal Cerebral Ischemia in the Rat

Background: The role of Renin Angiotensin System (RAS) in ischemic/reperfusion (I/R) injuries is not fully elucidated. Furthermore, it is not clear whether inhibition of RAS by Angiotensin-Converting Enzyme (ACE) inhibitors has beneficial effects in terms of protecting the brain from I/R injuries. In this study enalapril is used as an ACE inhibitor to evaluate the role of RAS in I/R injuries in...

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inhibition of angiotensin-converting enzyme reduces cerebral infarction size in experimental-induced focal cerebral ischemia in the rat

background: the role of renin angiotensin system (ras) in ischemic/reperfusion (i/r) injuries is not fully elucidated. furthermore, it is not clear whether inhibition of ras by angiotensin-converting enzyme (ace) inhibitors has beneficial effects in terms of protecting the brain from i/r injuries. in this study enalapril is used as an ace inhibitor to evaluate the role of ras in i/r injuries in...

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Deficiency of intercellular adhesion molecule 1 attenuates microcirculatory disturbance and infarction size in focal cerebral ischemia.

Recent evidence has shown crucial roles for cell-adhesion molecules in inflammation-induced rolling, adhesion, and accumulation of neutrophils in tissue. Intercellular adhesion molecule-1 (ICAM-1) is one of these adhesion molecules. Previous studies have shown marked reduction in the size of infarction after focal cerebral ischemia by depletion of granulocytes and administration of the antibody...

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Neonatal cerebral infarction presented with limb ischemia.

Cerebral infarction of newborn infants is a rare condition. It remains the least predictable etiology of neonatal seizures, and the appreciation of its occurrence among physicians needs to be re-addressed. The most common presenting feature is seizure. We report 2 full term newborn infants who developed middle cerebral infarction. These infants presented primarily with ischemic limbs for severa...

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ژورنال

عنوان ژورنال: Stroke

سال: 2003

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.0000083400.80296.38